Collects Marvel Universe Ultimate Spider-Man Vs. The Sinister Six #1-4.

Featuring screen-capture images from MARVEL'S ULTIMATE SPIDER-MAN VS. THE SINISTER SIX! Spider-Man faces fearsome foes and finds fabulous friends! With Spider-Verse and Contest of Champions behind him, things are looking up for Peter Parker, right? Wrong! Because Doctor Octopus + Arnim Zola + Baron Mordo + Hydra = Trouble. Huge trouble! S.H.I.E.L.D. is down! The Web-Warriors are no more! So Spidey's gonna need some new pals. How about Scarlet Spider, Doctor Strange and Miles Morales?! But when Peter and Miles share the ultimate Spider-Man team-up, can the more experienced wall-crawler stop being overprotective long enough to take out Doc Ock? And what does Norman Osborn have to do with Otto Octavius' nefarious plan?