Venerable Doboom Lozang Tenzin Tulku was born in 1942 in Kham in eastern Tibet. At the age of two or three, he was recognized as the reincarnation of the previous Doboom Tulku. Following this, he was taken to stay at a hermitage near Dargye Monastery where he stayed until the age of twelve. In 1953, Doboom Tulku entered Drepung Monastery in Lhasa, where he studied Buddhist philosophy until the Chinese invasion of Tibet in 1959 forced him into exile in India at the age of seventeen. For the following decade, Doboom Tulku resided at the lama camp at Buxa Duar, in West Bengal, enduring harsh conditions until he joined the Institute of Higher Tibetan Studies at Sarnath in 1969. Continuing with his studies in Sarnath, he obtained a Geshe Acharya degree in 1972.
After obtaining his degree, he worked as a librarian at Tibet House in New Delhi, until he joined the Library of Tibetan Works and Archives in Dharamsala as a librarian and research assistant in 1973. By 1981, having gained more experience, he returned to Tibet House, New Delhi, to serve as director, with the mission of promoting Tibetan cultural heritage through Tibet House's diverse range of programmes. Doboom Tulku served as director of Tibet House for 30 years.

Doboom Tulku has also worked with His Holiness the Dalai Lama's Private Office and has accompanied His Holiness the Dalai Lama on visits to the USA, USSR, Japan and Mongolia among others. He has published widely, on topics ranging from Tibetan medicine to Buddhist meditation and the Chittamatra Mind-Only School of philosophy. In 1996, he founded the World Buddhist Culture Trust for bridging cultures and promoting religious dialogue and harmony on the basis of universal compassion. He also had a personal interest in the effects of music for spiritual practice and worked hard at setting up the World Festival of Sacred Music, which became a global event.

Doboom Tulku passed away in January 2024.